US secretary of state John Kerry is scheduled to have surgery on his broken leg at Massachusetts General Hospital in Boston.
The State Department said that before the surgery, Mr Kerry will participate by telephone in an international gathering on how to combat Islamic State in Paris.
He suffered the injury in a bike accident on Sunday, when he struck a curb and fell on a regular Tour de France route south-east of Geneva. He has returned to Boston for the surgery.
Mr Kerry had planned to travel to Madrid on Sunday for meetings with Spain's king and prime minister, and then spend two days in Paris for the meeting on Islamic State.