What are the triggers behind hospital figures across Ireland showing the extent to which the coronavirus is particularly dangerous for patients with some existing illnesses?
Heart disease is the most common condition among patients who end up in intensive care, followed by long-term respiratory disease, diabetes, obesity, cancer and chronic kidney disease.
Doctors say when it comes to patients with cardiac and circulatory disease, the lungs are the most common organ to be affected by the coronavirus.
The virus causes infection of the lungs, a pneumonia.
When the lungs get an infection the air spaces become filled with fluid, and this leads to inflammation. It means the body must work harder to get oxygen into the blood.
Strain on the heart
The fact the heart and lungs operate in tandem means the heart then has to work harder and this puts additional pressure on patients who have a pre-existing disease.
Doctors say patients with heart disease are not more likely to catch the virus, but they are at a higher risk of complications if they do.
According to medics, people with diabetes have lowered immune systems and this makes them less able to fight infection. The additional strain from the infection can affect a diabetic's heart and kidneys.
People who have cancer have a lowered immune system because of the disease or treatment. They could also be at risk if they are having radiotherapy for lung cancer.
The Irish Cancer Society said blood cancers that affected bone marrow can also hurt the immune system.
Immune inhibition from treatments is usually short-lived and normal immunity recovers after several weeks.
Not all cancer treatments will compromise the immune system.
It is still unclear why obese people are at a higher risk from the coronavirus. Some doctors say it could be linked to lowered lung function and more inflammation of the fatty tissue around internal organs.
Obese patients can have breathing difficulties. The additional weight they are carrying can make it more difficult for the lungs to expand and inhale oxygen. The virus may lead to the immune response going in to overdrive.
People with kidney disease are more likely to have heart problems and high blood pressure. This will put stress on the lungs. People who have had a kidney transplant will be on drugs to ensure the body's immune system does not reject the new kidney.
Higher risk for men
More men than women are dying of the coronavirus in Ireland. This is also seen in other countries.
Some scientists point to the fact that a number of critical immune genes are located on the X chromosome.
Because women have two copies of this chromosome and men only one, it means women may be better equipped to fight infection and viruses.
There are no figures here to show the ethnicity of those who have died from the virus.
But a new study from the University of Oxford and the London School of Hygiene & Tropical Medicine found people of Asian and black ethnic backgrounds in the UK are at a higher risk of death.
Contrary to prior speculation, this is only partially attributable to pre-existing clinical risk factors or deprivation.