Where and when is it on?
The game takes place at Goodison Park in Liverpool with a 7.00pm kick-off on Sunday.
Where can I watch the game?
The match will be shown live on BT Sport 1 from 6.30pm. The game is also being streamed live on the BT Sport Player.
What is the head-to-head record like?
It was way back on 24 September 1892 that the clubs first faced off with Everton easy 6-0 winners in an old Division One clash. It took Man United eight games to claim their first win, coming out on the right side of a seven-goal-thriller in the top flight on 9 March 1907.
Of 206 games played to date, 90 have ended in Man United wins, with 68 Everton victories and there's been 48 draws.
Last season's matches finished in a 1-1 draw at Old Trafford and a 1-0 win for the Toffees at Goodison.
What's the team news?
Everton striker Dominic Calvert-Lewin is set for his first involvement of the season at home to Manchester United.
The England international was sidelined by a knee injury on the eve of the opening weekend but is now fit enough to join the squad.
Defenders Yerry Mina and Mason Holgate have returned to training after respective ankle and knee injuries.
United defender Raphael Varane faces a race to be fit in time for the trip to Goodison Park.
The France international went off in the first half against Manchester City last weekend with an ankle complaint that ruled him out of Thursday’s Europa League win at Omonia Nicosia.
United captain Harry Maguire joins Aaron Wan-Bissaka and Donny van de Beek in being sidelined again, while Brandon Williams and Axel Tuanzebe are long-term absentees.
Everton provisional squad: Pickford, Coleman, Tarkowski, Coady, Mykolenko, Gueye, Onana, Iwobi, Gordon, Maupay, Gray, Begovic, Keane, Vinagre, McNeil, Doucoure, Davies, Mills, Garner, Calvert-Lewin, Rondon
Manchester United provisional squad: De Gea, Heaton, Dubravka, Dalot, Varane, Lindelof, Martinez, Malacia, Shaw, Fred, Casemiro, McTominay, Eriksen, Fernandes, Iqbal, Pellistri, Elanga, Garnacho, Antony, Sancho, Ronaldo, Martial, Rashford,
What can I read about in the build-up on Independent.ie?
Man United returned to winning ways on Thursday night but were far from convincing once again in their 3-2 comeback win over Neil Lennon's Omonia Nicosia.
The post mortem into the Red Devils' humiliation in Sunday's Manchester derby continues, with James Ducker detailing here why Roy Keane was right in his assertion that the club have disrespected Cristiano Ronaldo in how he's been treated this season.
Eamonn Sweeney also gave his thoughts after the game which are below alongside the match report.
Everton claimed only their second win of the season last Saturday with a 2-1 comeback at Southampton, a game which saw Seamus Coleman return to the starting XI.
What are the match odds?
Man United are favourites at 19/20 with Everton 11/4 and the draw priced at 12/5.
What are the managers saying?
“Yes, he (Calvert-Lewin) is in contention.
“We’ll have to see how match-fit he is, but in terms of the injury he’s better. It’s a really good boost.
“He’s a good player for us, pivotal in us staying in the league last year and we want to get him playing regularly.”
Erik ten Hag:
“I know what nasty is. I think also in that matter we can progress. Sometimes also play a little bit more smart.
“We have too many bookings and some in the start. I heard, yeah, in the Premier League they will play tough but I’m really wondering why we collect so many bookings and I don’t understand.
“Like the first booking on Sunday, I really don’t understand that when we want to play tough, we want to keep the game going.
“Then in the second minute already it’s a booking for (Dalot). I think it’s a duel, clear it was a foul, but then get booked? Also I saw many other bookings where I think ‘OK, is that necessary’?
“But also I take it to the players. I have to keep the mirror (on them) that they have to play smart, but also, hey, they have to play nasty as well.”