CLAUDIO Ranieri last night resigned as manager of Roma after his side squandered a three-goal lead to lose 4-3 to Genoa.
The result comes on the back of a dreadful run of form that saw the men from the Italian capital slip to a 5-3 defeat to Inter, as well as losing 2-0 to Napoli and 3-2 at home at Shaktar Donetsk in the Champions League.
The run of defeats saw protests outside Roma's training centre by fans last week.
Roma now sit eighth in the league and yesterday's capitulation proved the final straw for the man who has coached the club since 2009.
Meanwhile, Serie A leaders AC Milan returned to winning ways with a Pato-inspired 2-1 victory over Chievo Verona. The Brazilian came off the bench to score the winner that helped the Rossoneri get over their midweek defeat to Tottenham. Second-placed Napoli beat Catania 1-0 to maintain the pressure.
Juve slipped to a 2-0 defeat at Lecce, while Inter's 1-0 win over Cagliari sees them keep pace with their city rivals.
Manchester United will be boosted by the news that Andre-Pierre Gignac will miss Wednesday's Champions League clash with Marseille at the Stade Velodrome after picking up an abductor strain in his side's 2-1 win over Saint Etienne on Saturday.
In La Liga, Barcelona needed a late goal from Lionel Messi to maintain their title charge with a hard-fought 2-1 victory over Athletic Bilbao.
David Villa gave Barca an early lead when he rounded off a well-crafted move, but Andoni Iraola's penalty five minutes after the interval gave the Nou Camp some nervous moments.
However, 12 minutes from time, Dani Alves found Messi at the near post and the Argentine finished neatly.
On Saturday, Real Madrid's 22nd successive home win saw them beat Levante 2-0. Indeed, it is now nine years since Mourinho last suffered a home league defeat.
In the Bundesliga, Hamburg agreed a deal to take Chelsea sporting director Frank Arnesen and chief scout Lee Congerton to the club.