Where and when is it on?
The game takes place at Elland Road with a 4.30pm kick-off on Sunday.
Where can I watch the game?
The match will be shown live on Sky Sports Main Event and Sky Sports Premier League with coverage starting at 4.00pm. The game is also being streamed live on the Sky Go app.
What is the head-to-head record like?
The clubs first met on 23 Feb 1924 in an FA Cup game won 3-0 by Villa. Leeds' first win came later that year with a 6-0 Christmas Day thrashing in the old Division 1.
Of 104 games played to date, 32 have ended in Leeds wins, 41 for Villa and there's been 31 draws.
Last season's matches finished in a thrilling 3-3 draw at Villa Park and a 3-0 win for Villa at Elland Road.
What's the team news?
Patrick Bamford, Rodrigo, Liam Cooper, Luke Ayling and Junior Firpo are all in contention for Leeds.
Bamford has only started two games this season due to injury and Rodrigo has recovered from a dislocated shoulder, while skipper Cooper (calf), Ayling and Firpo (both knee) are all hoping to make their first league starts.
Adam Forshaw (ankle) and teenager Archie Gray (fractured toe) are out while Stuart Dallas (fractured femur) remains a long-term absentee.
Aston Villa will be without France midfielder Boubacar Kamara, who suffered knee ligament damage in the win over Southampton before the international break which will rule him out of the World Cup.
Left-back Lucas Digne (heel) was also forced to pull out of France’s squad and will miss the trip to Elland Road, but Jan Bednarek, on loan from Southampton, is available again after being ineligible to face his parent club.
Matty Cash (hamstring) is set to resume full training next week while centre-back Diego Carlos continues his rehabilitation from a ruptured Achilles.
Leeds provisional squad: Meslier, Robles, Klaesson, Koch, Llorente, Struijk, Kristensen, Ayling, Hjelde, Cooper, Firpo, Drameh, Roca, Harrison, Adams, Aaronson, Klich, Gyabi, Sinisterra, Summerville, Rodrigo, Bamford, Gelhardt, Greenwood.
Aston Villa provisional squad: Martinez, Konsa, Mings, Young, Bednarek, McGinn, Coutinho, Ramsey, Buendia, Watkins, Bailey, Olsen, Chambers, Augustinsson, Dendoncker, Luiz, Sanson, Nakamba, Ings, Archer
What can I read about in the build-up on Independent.ie?
Former Leeds and Villa midfielder Fabian Delph has retired from football at the age of 32.
Leeds' last two games were postponed after the death of Queen Elizabeth II so they've had to wait to try and get over a chastening 5-2 defeat to Brentford at the start of September.
Villa's last outing ended in a much needed win over Southampton which has eased some of the pressure that had been building on Steven Gerrard.
What are the match odds?
Leeds are favourites at 13/10 with Villa 2./1 and the draw priced at 12/5.
What are the camps saying?
“Togetherness and commitment here is the highest I have seen. I don’t want to leave.
"If I got an offer to go anywhere I would stay in this spot. More happy than I have ever been in my career.”
“We took four points from six and seemed to have turned the corner, our form has improved and I would like to have carried on.
“We have got a lot of games now until the World Cup, a lot of opportunities for us to pick more points up and that is the plan.”