Liverpool will not go unbeaten throughout this Premier League season, defeat at Manchester City ensuring Arsenal's 'Invincibles' remain untouched for another year.
Here, we look at how far their unbeaten run went.
1 - August 12, Liverpool 4 West Ham 0
An easy opening-day win at Anfield with Mo Salah opening the scoring, Sadio Mane firing a brace and Daniel Sturridge also getting on the scoresheet at Anfield.
2 - August 20, Crystal Palace 0 Liverpool 2
James Milner's 45th-minute penalty gave Liverpool the lead at Selhurst Park, but the win was not confirmed until Mane's last-minute goal against 10-man Palace.
3 - August 25, Liverpool 1 Brighton 0
The home side enjoyed 70 per cent of the possession but only had Salah's first-half goal to show for their domination.
4 - September 1, Leicester 1 Liverpool 2
Rachid Ghezzal became the first player to score against the Reds in the Premier League, but by then the home side were already 2-0 down thanks to goals from Mane and Roberto Firmino in the first half.
5 - September 15, Tottenham 1 Liverpool 2
Goals from Georginio Wijnaldum and Firmino either side of half-time ensured Jurgen Klopp's side passed their biggest test of the season so far, with Erik Lamela scoring a last-minute consolation at Wembley.
6 - September 22, Liverpool 3 Southampton 0
An early own-goal from Wesley Hoedt set the home side on their way to a comfortable win, with Joel Matip and Salah completing the scoring in the first half.
7 - September 29, Chelsea 1 Liverpool 1
Having lost to the same opposition in the EFL Cup just three days earlier, Liverpool looked set for a second straight loss until Sturridge cancelled out Eden Hazard's opener with a stunning 89th-minute strike.
8 - October 7, Liverpool 0 Manchester City 0
Both sides extended their unbeaten start to eight games, but City were left to rue Riyad Mahrez blazing a late penalty over the bar after Leroy Sane was brought down by Virgil Van Dijk.
9 - October 20, Huddersfield 0 Liverpool 1
Salah's 50th goal in English football was enough to secure all three points against Huddersfield, who had Alex Pritchard's goal ruled out for offside.
10 - October 27, Liverpool 4 Cardiff 1
Goals from Salah and Mane seemingly put the home side in command, but Callum Paterson scored from Cardiff's only shot on target before late strikes from Mane and Xherdan Shaqiri made certain of the points.
11 - November 3, Arsenal 1 Liverpool 1
Liverpool looked on course for victory when Milner broke the deadlock just after the hour mark, but Alexandre Lacazette earned the home side a point with an equaliser eight minutes from time.
12 - November 11, Liverpool 2 Fulham 0
Salah opened the scoring just 14 seconds after Aleksandar Mitrovic controversially had a header ruled out for offside, with Shaqiri sealing the win early in the second half.
13 - November 24, Watford 0 Liverpool 3
A stunning free-kick from Trent Alexander-Arnold was the highlight of a superb second-half display at Vicarage Road which was marred only by a red card for captain Jordan Henderson.
14 - December 2, Liverpool 1 Everton 0
Divock Origi scored the winner in the 96th minute after Everton goalkeeper Jordan Pickford mishandled a skied shot from Van Dijk, leaving Origi to head into an empty net.
15 - December 5, Burnley 1 Liverpool 3
Jack Cork gave the home side a surprise lead after 54 minutes, but a much-changed Liverpool side hit back through goals from Milner, Firmino and Shaqiri.
16 - December 8, Bournemouth 0 Liverpool 4
Salah was offside when he opened the scoring after 25 minutes, but there was nothing fortunate about the rest of his second hat-trick for the club in a comfortable win.
17 - December 16, Liverpool 3 Manchester United 1
Jesse Lingard cancelled out Mane's opener against the run of play at Anfield, but substitute Shaqiri scored twice in seven minutes to give the home side a deserved win in what proved to be Jose Mourinho's last game in charge.
18 - December 21, Wolves 0 Liverpool 2
Goals from Salah and Van Dijk gave the visitors a victory which ensured they would be top of the Premier League table on Christmas Day.
19 - December 26, Liverpool 4 Newcastle 0
Dejan Lovren was the unlikely first scorer with a thunderous half-volley and further goals from Salah, Shaqiri and Fabinho made for an easy win against the Magpies.
20 - December 29, Liverpool 5 Arsenal 1
Arsenal struck first at Anfield through Ainsley Maitland-Niles, but Firmino scored twice in the space of two minutes and later completed his hat-trick from the penalty spot, with Mane and Salah also on target in the rout.
Liverpool manager Jurgen Klopp declared Manchester City captain Vincent Kompany should have been sent off for his flying first half tackle on Mohamed Salah, after his side slipped to their first defeat of the Premier League season at the Etihad Stadium.
Liverpool are unbeaten in the league having dropped just six points this season and go into the match on a nine-match winning streak and a seven-point lead over Pep Guardiola's team. Follow all the action from the Etihad here