FA Cup weekend should offer some Irish youngsters the opportunity to build their first team experience with managers likely to rest senior men.
Cavan prospect Jake Doyle-Hayes is expected to figure for Aston Villa in their home tie with League One side Peterborough.
The teenage midfielder was involved in both of Villa's EFL Cup games and was on the bench for last week's Championship win at Middlesbrough.
"I'm telling the supporters now that four or five young ones will play because they could be the future of the club," said Villa boss Steve Bruce.
New Ipswich signing Aaron Drinan will be on the bench for the visit of Sheffield United. Mick McCarthy has confirmed that the ex-Cork City and Waterford striker is in contention after formalising his move this week.
The 19-year-old has been training with Ipswich since October and not looked out of place.
"He's had a spring in his step ever since he's been here, and he's had an even bigger spring in his step the last week now that he can actually play," said McCarthy, who admitted that Irish attacker David McGoldrick could leave this month.
McGoldrick is out of contract at the end of the season and is wanted by Cardiff. "He is an obvious target and none of us want to lose him but we'll see what happens," said McCarthy.
Irish U-21 international Corey Whelan could be eligible for Yeovil's meeting with Bradford after completing a loan move from Liverpool.
Declan Rice will further his West Ham education at Shrewsbury tomorrow after starring in Thursday's Premier League draw with Spurs and winning praise from David Moyes: "He's got a great attitude, he's committed and I think he'll get better because he's a really good boy to work with."