Buffon and Barzagli sit out Juve's shock loss
Juventus suffered a shock 3-2 defeat at Sampdoria after resting veteran 'keeper Gianluigi Buffon and defender Andrea Barzagli, because "they needed time to get over" Italy's World Cup play-off disaster.
Juve boss Massimiliano Allegri rested the pair, who both called time on their international careers following the play-off defeat to Sweden.
Duvan Zapata, Lucas Torreira and Gian Marco Ferrari put Sampdoria 3-0 up in the second half before Juventus threatened a stoppage-time comeback with a penalty from Gonzalo Higuain and a strike from Paulo Dybala.
Juve's first came from a penalty after Ivan Strinic fouled Douglas Costa - and then Dybala smashed home with seconds left.
But it proved too late for Juve as they failed to secure victory ahead of their Wednesday night Champions League clash against Barcelona in Turin.
Barca, meanwhile, said they will appeal the yellow cards shown to Gerard Pique and Luis Suarez in Saturday's 3-0 win over Leganes.
Pique was booked in the first half for a slight pull on Nordin Amrabat. Leganes goalkeeper Cuellar had put an arm across Suarez neck, before the Uruguayan raised an arm to remove the 'keeper's and Cuellar had gone to ground holding his face.
The former Liverpool striker ended his drought with two goals before a late strike from Paulinho ensured their unbeaten run extended to 12 games.
Elsewhere, Atletico Madrid and Real Madrid shared a rare goalless draw in the first derby at the new Wanda Metropolitano stadium.
Sevilla's Luis Muriel and Nolito scored either side of half-time in their 2-1 victory over Celta Vigo on Saturday ahead of their Champions League clash with Liverpool tomorrow.
In France, Edinson Cavani maintained his prolific goalscoring form with two more as Paris Saint-Germain beat Nantes 4-1 ahead of PSG's European clash with Celtic on Wednesday.
In Switzerland, FC Basel enjoyed a 5-1 triumph over Sion before their clash with Manchester United.
Ahead of their tie with Manchester City tomorrow night, Feyenoord drew 1-1 with VVV-Venlo in the Eredivisie.