Harry Arter is one of six players to have been ruled out of Ireland's World Cup qualifier against Wales on Friday due to a calf injury.
The Bournemouth midfielder missed Saturday's win over Swansea City with Cherries boss Eddie Howe afterwards casting doubt of the player's ability to recover in time to feature for Martin O'Neill's side.
“I would have thought there’s no way he’ll play," said Howe.
It's understood Arter has conceded defeat in his bid to be fit and will concentrate on his rehab during the international break to ensure he's back for Bournemouth's Premier League run-in.
His unavailability is all the more disappointing as he was likely to start in midfield having impressed on his competitive debut in Austria last November.
Instead of joining up with Ireland, Arter has flown to Dubai with the rest of the Bournemouth squad for a training camp and was pictured on the flight when Benik Afobe shared a picture on social media earlier today.
Elsewhere, Rob Elliot (knee), Paul McShane (hamstring), Ciaran Clark (knee), Liam Kelly (hamstring), and David McGoldrick (knee) miss out through various injuries.
Midfielder Robbie Brady will remain with the squad in spite of being suspended for the Wales game, as he will be available for the friendly with Iceland on Tuesday, 28 March at the Aviva Stadium.