Arsenal had two men sent off at Stamford Bridge as Barclays Premier League champions Chelsea recorded their first home league triumph of the season in a 2-0 success.
Gunners central defender Gabriel was dismissed following a series of running battles with the combative Diego Costa before midfielder Santi Cazorla also received his marching orders after being awarded two yellow cards.
Kurt Zouma headed home the opener in between the red cards and Eden Hazard's effort deflected off Calum Chambers late on as Jose Mourinho's impressive record against rival boss Arsene Wenger continued.
Saido Berahino scored for the winner for West Brom in their midlands derby with Aston Villa less than three weeks after he stated he would never play for Baggies chairman Jeremy Peace again.
The 22-year-old made that declaration during a Twitter rant after a deadline-day move to Tottenham failed to materialise.
However, after coming on in last weekend's 0-0 draw with Southampton, he started at Villa Park and struck in a 1-0 win just before half-time, deflecting James Morrison's effort beyond goalkeeper Brad Guzan.
Newcastle, Sunderland and Stoke's winless streaks were all extended to six games as none of the trio were able to move out of the relegation zone.
Leicester boss Claudio Ranieri had promised pizza to his side if they kept a clean sheet at the Britannia Stadium, yet that incentive did not stop Potters forward Bojan Krkic, starting a league game for the first time since January, and Jonathan Walters finding the net inside 20 minutes.
Ranieri's side staged a come-from-behind victory against Aston Villa last weekend and six days on they fought back again to draw 2-2, Riyad Mahrez converting a penalty for his fifth of the season before Jamie Vardy levelled.
Sunderland prop up the division as they were undone by a two-goal blitz inside the opening nine minutes in a 2-0 loss at Bournemouth.
Callum Wilson scored for the fifth time in this campaign and Scotland international Matt Ritchie then scored a brilliant second, chesting and volleying in after a semi-cleared corner had reached him 25 yards out. Black Cats defender Younes Kaboul was then sent off for a pair of cautions on another dismal afternoon for Dick Advocaat's side.
Odion Ighalo's brace in the first 28 minutes gave Watford a 2-1 away triumph at Newcastle.
The Nigeria international claimed the winner against Swansea last weekend and his good form after signing a new deal continued in the north east, where Daryl Janmaat managed to pull one back in the second period.
In the other 3pm kick-off, the spoils were shared in south Wales as Everton boss Roberto Martinez's return to old club Swansea resulted in a goalless stalemate.
Toffees forward Kevin Mirallas picked up the fourth red card of the day for a wild lunge on Modou Barrow that came less than two minutes after he had been introduced as a substitute.
In the late kick-off, leaders Manchester City dropped points for the first time this season in losing 2-1 to West Ham at the Etihad Stadium.
City had not conceded in their opening five contests but Chelsea loanee Victor Moses and Diafra Sakho put the ball past goalkeeper Joe Hart in the opening 31 minutes.
Belgium international Kevin De Bruyne pulled one back on the stroke of half-time on his full debut, but the Hammers withstood second-half pressure to record another impressive away victory having already defeated Arsenal and Liverpool on their travels this term.
The win moved West Ham up to second, three points behind City.