Liverpool manager Brendan Rodgers admits Daniel Sturridge has to be handled carefully to ensure they do not "break" him again.
The England international missed six months of last season with a number of injuries, resulting in him undergoing a hip operation in May in an attempt to cure underlying issues.
He has made his comeback in Liverpool's last two matches, showing a familiar sharpness in scoring twice in Saturday's 3-2 win over Aston Villa.
However, with the Merseyside derby at Everton looming on Sunday he will not be involved in Thursday's Europa League tie at home to Sion.
"We have seen from the game at the weekend he is still building his way towards full fitness," said Rodgers.
"With every individual player you have to assess and analyse where they are physically.
"Daniel has worked very hard and has come back ahead of schedule but we just have to make sure we don't break him at this stage.
"He won't be involved in the game, which will keep him fresh and help work towards his fitness for the weekend."
Roy Hodgson names his England squad tomorrow and Sturridge is likely to be in contention after his return to fitness.
It was this time last year the 26-year-old sustained a thigh problem while training with the national team which signalled the start of his injury problems.
It was an issue which also pitted club versus country as Liverpool were unhappy with the way their striker - who has a two-day recovery programme after matches to help lessen his injury risk - was handled.
There is unlikely to be a repeat this time around with dialogue set to take place between the two.
"I haven't spoken to them (the FA) as yet. At this moment in time the concern is making sure he is fit and ready for Liverpool," added Rodgers.
"But Daniel is back in the fold now and he is obviously one of the top English strikers so if he is back fit and performing I'd expect him to be chosen for the national team."
Sturridge's absence from the squad is likely to give youngster Divock Origi another chance up front.
The Belgium international, a £10million signing last year, has struggled for game time having returned from a season on loan at former club Lille and is still looking for his maiden Reds goal.
He started in Liverpool's opening Europa League tie in Bordeaux but was isolated up front and since then has only 55 minutes as a substitute against League Two Carlisle in the Capital One Cup.
The 20-year-old has scored just five goals - which includes a hat-trick - in his last 39 appearances for club and country but Rodgers is unconcerned.
"It just takes time to adapt. He is a young player who has excellent qualities," he said.
"Divock will be judged on goals and games but he hasn't really played much but he understands where he is at coming into such a big club.
"It is about nurturing that talent and he is looking to improve that goalscoring record, which will hopefully come with time.
"He is a humble guy. He knows where he stands, he knows he's here to develop and he knows he's come to a prestigious club.
"He knows he will get opportunities and has settled in very well.
"He had his loan period last year and this season it was about him coming into the club.
"We will review where he is at the end of the season."