Tommy Bowe has revealed his frustration surrounding the botched try opportunity in the second half which would have put Ireland in front against Wales during their 23-16 defeat in Cardiff.
Substitute centre Scott Williams' second-half try proved the difference in comfortably the best game of this season's championship, while full-back Leigh Halfpenny kicked five penalties and fly-half Dan Biggar dropped a goal.
Ireland responded with a 69th-minute penalty try, plus 11 points from fly-half Johnny Sexton's boot, but they suffered a first defeat in 11 Tests and only their third since coach Joe Schmidt took charge almost two years ago.
One of the big turning points in the game was when Ireland failed to convert an attack in the Welsh 22 in the second half when they trailed 20-9 in the 65th minute.
Eoin Reddan had been pulled into the ruck and Ireland had a massive overlap on the wing but the ball wasn't delivered and Cian Healy lost the ball forward with the line at Ireland's mercy.
"We were screaming for it out wide but the noise and the atmosphere in that stadium... it's very hard to hear anything. I think our scrum half was in the ruck," he said.
"It's something that we work on but when you that close to the line , I'm sure what's going through their heads is get over the line and score.
"These are the small margins, whenever we give a 12-point lead to a team of the class of Wales, to be playing catch-up, you really need to take your chances when you get them."
Ireland can still win the Championship but they will need to beat the Scots in Murrayfield next week and hope our points difference is good enough to lift the trophy.
Bowe added: "We'll be hurting now, we'll be disappointed 100pc in the changing room, the boys are very, very quiet in there with what we let slip.
"We'll come back into camp, we're straight back to Carton House tomorrow, we've got it all to play for. The first opportunity for an Irish team to win back-to-back titles in I don't know how long.
"It's a massive match in Murrayfield next week and we'll be pumped up for it."
Ireland's Grand Slam hopes died in Cardiff but Joe Schmidt's men will still go into the last match of this year's Six Nations tournament next weekend in contention for the Championship. Here is how the players rated against Wales today.
Ireland's search for a record-breaking 11th successive victory and the third Grand Slam in their history came to a halt when they succumbed to Wales 23-16 at the Millennium Stadium in Cardiff today.