Andy Farrell is expected to keep faith with the same starting Ireland team who beat Wales for this Sunday's Six Nations clash against England.
That would mean the head coach will resist the temptation to put the fit-again Caelan Doris straight back into the XV as Peter O'Mahony is rewarded for his recent resurgent form.
Doris is set to be named amongst the replacements in place of Max Deegan, who is likely to drop out of the match-day 23 for the trip to Twickenham.
Having impressed off the bench in the win over Wales two weeks ago, Keith Earls is pushing hard for a recall, but the Ireland back-three now has a settled look to it with Jordan Larmour, Andrew Conway and Jacob Stockdale. As a result, Earls may have to make do with a place on the bench again.
With Garry Ringrose again missing out with a thumb injury, the midfield picks itself as Bundee Aki and Robbie Henshaw will renew their centre partnership.
Conor Murray is playing much more like his old self again, which has lessened the calls for John Cooney to start, and the Munster scrum-half is in line to continue alongside captain Johnny Sexton.
Up front, Cian Healy looks to have edged out Dave Kilcoyne for a starting spot as the Limerick man continues to force the issue.
Ronan Kelleher got some much-needed game-time under his belt in Leinster's win over the Cheetahs last weekend, but Rob Herring has played well in the opening two Six Nations wins, and is likely to keep his place in the front-row alongside Healy and Tadhg Furlong, who is also looking back to his best.
A familiar-looking engine room will see Iain Henderson and James Ryan link up, while behind them, O'Mahony, Josh van der Flier and CJ Stander are set to make-up what is very much a tried and tested back-row.
Ireland will officially name their team to take on England tomorrow at 1.50pm.
Possible Ireland team to play England on Sunday – J Larmour; A Conway, R Henshaw, B Aki, J Stockdale; J Sexton (capt), C Murray; C Healy, R Herring, T Furlong; I Henderson, J Ryan; P O'Mahony, J van der Flier, CJ Stander.