Munster boss Johann van Graan has made wholesale changes for his side's Pro14 clash against Dragons at Rodney Parade on Saturday.
With a host of names preparing for next week's Six Nations opener against England, Van Graan has made 13 changes from the team that beat Exeter in the Champions Cup last weekend.
Tyler Bleyendaal captains the team from inside centre with full-back Mike Haley and lock Jean Kleyn the only starters from the Exeter clash to keep their places.
Darren Sweetnam and Ronan O'Mahony are named on the wings with Bleyendaal and Dan Goggin forming the centre partnership.
Alby Mathewson and Bill Johnston are named in the half-backs.
Jeremy Loughman, Rhys Marshall and Stephen Archer pack down in the front row with Archer making his 180th appearance for the province.
Kleyn and Billy Holland start in the engine room with a back row of Fineen Wycherley, Conor Oliver and Arno Botha completing the side.
Prop Liam O'Connor is in line to make his first PRO14 appearance of the season after recovering from a long-term knee injury with Academy man Gavin Coombes also among the replacements.
Munster: Mike Haley; Darren Sweetnam, Dan Goggin, Tyler Bleyendaal (C), Ronan O’Mahony; Bill Johnston, Alby Mathewson; Jeremy Loughman, Rhys Marshall, Stephen Archer; Jean Kleyn, Billy Holland; Fineen Wycherley, Conor Oliver, Arno Botha.
Replacements: Kevin O’Byrne, Liam O’Connor, Ciaran Parker, Darren O’Shea, Gavin Coombes, Neil Cronin, Calvin Nash, Jaco Taute.
Regardless of what happens in the next 10 weeks, Joe Schmidt will finish his Six Nations career as one of the tournament's greatest coaches. Three titles in five years, with a Grand Slam in the mix, guarantees his legacy in the competition.