Young Munster are third in the Ulster Bank League Division 1A as they make the daunting trip to the Aviva Stadium where they will face the in-form Lansdowne tomorrow.
John Staunton's men made a similar journey east last weekend where they fell to a disappointing 21-15 defeat to St Mary's at Templeville Road.
On that occasion their discipline let them down as Cathal Marsh struck over seven penalties for the opposition and they know they cannot afford to give Lansdowne the same opportunities.
Lansdowne beat league leaders Terenure and ended their 29-game winning streak last weekend and are five points clear of Young Munster in the standings.
Cork Con also travel to Dublin where they face UCD in the Belfield Bowl tomorrow.
Con are one place ahead of their rivals this weekend and after a 13-10 win over reigning champions Clontarf, confidence is high in Tom Tierney's side.
Dolphin host St Mary's and will fancy their chances if victory this weekend.
In 1B, Garryowen are very much on the upward curve and they travel to take on Malone in the hope that they can make ground on Galwegians who are top.
Shannon travel to play Ballymena in what could be a tough encounter while UL Bohs will be hoping to notch a needed victory when they host Buccaneers tomorrow as the competition moves to a crucial stage.