Nairo Quintana crashed out of the Vuelta A Espana on Wednesday after the Colombian Movistar rider suffered a second fall in as many days during the 11th stage.
Quintana was leading the overall standings heading into Tuesday's time trial but a spectacular high-speed tumble led to him dropping down to 11th, nearly 3-1/2 minutes behind Spaniard Alberto Contador, who took over the leader's red jersey.
Quintana "feels pain in his right-hand shoulder and has been moved by ambulance to a medical center to check on any fractures," Movistar said on their Twitter feed (@Movistar_Team).
The incident happened around the 20-kilometre mark of Wednesday's 154.4-km stage, which started in Pamplona and finishes after a steep climb to San Miguel de Aralar.
Watch the crash below: