Ireland coach Mark Aston has named six uncapped players in a 19-man squad for Saturday's match against England Knights at Langtree Park.
The squad includes six home-grown players in Wayne Kerr, Joe Taylor, Paddy Barcoe, Ian Cross, Aaron McCloskey and Adam Hughes, who is one of the new faces.
Leeds Rhinos academy player Sean Casey is hoping to follow in the footsteps of father Leo and brother Callum who have both represented Ireland.
Ireland (squad) -- W Kerr (Country Cowboys), E Cosgrove (Dewsbury), A Hughes, JA Taylor, P Barcoe (all Dublin City Exiles), L Finn, M Haley (both Featherstone), S Casey (Leeds), J O'Callaghan (London Broncos), P Smith (Sheffield Eagles), A McCloskey, I Cross (both St Helen's), D Bridge, J Mendicka, T McCarthy (all Warrington), A Mullally, D Allen, K Haggerty (all Widnes), J O'Donnell (Wigan).
ENGLAND full-back Mike Brown is "broken" and "gutted" after being ruled out of the rest of the Test series against South Africa.
The 26-year-old is returning home after suffering thumb ligament damage in Saturday's 22-17 loss in Durban. Nick Abendanon has been called up as a replacement.
Centre Brad Barritt will miss at least the second Test after an operation to repair a cut eyeball.
South Africa full-back Zane Kirchner has also been ruled out of the second Test with a knee injury.
DAVID Gillick made little improvement on his second comeback race in Moscow last night, finishing last in the 400m in 48.27, fractionally faster than his 48:36 run in Turin last Friday.
Dublin high jumper Deirdre Ryan cleared 1.83m to finish eighth at the same meeting, well below her 1.95m Irish record last summer that qualified her for the Olympics.
Meanwhile, Christine Ohuruogu has confirmed the Aviva London Grand Prix on July 14 will be her last major race before the Olympics.
The 28-year-old will compete at Crystal Palace ahead of the defence of her 400m crown.
The Londoner is coming into form after running a season's best 50.69 seconds in New York on Saturday.