Last year's winner McCambridge clocked a time of 02:34:19, just four seconds behind winner Esther Wanjiru Macharia of Kenya.
In the men's event, Eliud Too from Kenya crossed the line in first place with a time of 2:14:48 as he headed the field of over 14,000 runners in this year's run.
Patrick Monaghan set a new record to win the wheelchair event.
It was the 35th running of the race and 10,000 Irish entrants were joined by over 4,000 competitors from overseas.
Runners followed a counter-clockwise loop that takes them past St Stephen’s Green, along the River Liffey and through the Phoenix Park twice.
The route dipped south across the Grand Canal, through Bushy Park and around UCD before finishing at Merrion Square.
Also among the participants this year was 83-year-old John Collins from Limerick who was running his 30th consecutive marathon.
He came first in the 80-84 age group with a time of 6:55:52.
The completion of today's SSE Airtricity Dublin Marathon marked the end of a remarkable journey for one Irishman.
Tony Mangan embarked on a challenge to run around the world four years ago and at around 3pm today, his lifelong ambition was fulfilled.
The 57-year-old Dubliner crossed the line in today's Marathon in a time of 06:08:30 completing a mind-boggling journey that has seen him run 50,000km in the last four years.
The finishing line of the 2010 SSE Airtricity Dublin Marathon was the starting point for Tony's journey.
The day after the 2010 Dublin Marathon Tony ran across Ireland as far as Dunquin, Dingle; the most westerly point in Ireland.
He then set off to Jog the World on a trip that would take him across North America, South America, Australasia and Asia, before returning to run through Europe last June.
Runners can check on their finishing position and time by clicking here.
Check out our exclusive SSE Airtricity Dublin Marathon pullout in tomorrow’s Irish Independent with galleries, stories and the finishing times for all the participants.