Sir Isaac Newton, who is as low as 10-1 for the Investec Derby, makes his eagerly-awaited reappearance in the Homeserve Maiden Stakes at Chester tomorrow.
The Galileo colt is a full brother to Ralph Beckett's Oaks runner-up Secret Gesture and made a very pleasing debut at Leopardstown in October for Aidan O'Brien.
He finished a half-length second to Dermot Weld's Zawraq, who is currently second favourite for Epsom.
Sir Isaac Newton faces seven rivals, including John Gosden's Derby entry Keble, who finished second to Intilaaq at Newbury last month.
"He's only had one run and we were taking our time with him. He's a horse we've thought a lot of and he has a lot of speed," O'Brien told At The Races.
"You wouldn't rule out an Irish Guineas with him, but he probably has a lot to learn in a short space of time if he is going to be a Classic horse having only had one run.
"We always feel they learn a lot in Chester and come out of it very well. We'll let that happen and deal with it after that.
"He's a horse with a lot of pace, he could come back to an Irish Guineas if we needed him - Magician did that (after winning at Chester)."