Tony McCoy will ride Cantlow for his boss JP McManus in the BoyleSports Irish Grand National at Fairyhouse on Monday.
The soon-to-retire champion has chosen the Paul Webber-trained 10-year-old over McManus's two other entries in the big handicap chase, top-weight If In Doubt, trained by Philip Hobbs, and Tom Mullins' Alderwood.
Cantlow finished eighth last year under Andrew McNamara as McManus lifted the prize with the Barry Geraghty-partnered Shutthefrontdoor.
McCoy will be hoping he can be triumphant in the famous green and gold colours and win the race for a second time, having been successful on Butler's Cabin in 2007.
Gallant Oscar is not among the final field. Though he had been ante-post favourite before being usurped by Cantlow, connections of the Tony Martin-trained 10-year-old are instead hoping he makes the cut for the Crabbie's Grand National on Saturday week.
Gallant Oscar also holds an entry in the Coral Scottish Grand National at Ayr a week later.
Robert Tyner's Embracing Change, winner of his last four races, is another high-profile absentee.
However, there is a very strong line-up, with Willie Mullins saddling Perfect Gentleman and Dogora as he bids to get on the roll of honour for the first time.
Jim Dreaper is double-handed with Los Amigos and Sizing Coal, with Grand Jesture, Pass The Hat, Vics Canvas and Lots Of Memories among the other interesting contenders.
Dan Skelton's Toby Lerone is first reserve, while the Noel Meade-trained pair of Bose Ikard and Ipsos Du Berlais take up the other two stand-by places.