Zawraq is set for a lengthy spell on the sidelines after X-rays revealed a fracture to his off-fore cannon bone.
Dermot Weld's unbeaten colt was set to head to Epsom as a major contender for the Derby, but was found to be lame earlier in the week and although initial X-rays and scans were inconclusive, he was not declared for the premier Classic.
Connections were hoping the injury was not serious, but racing manager to Sheikh Hamdan Al Maktoum, Angus Gold, revealed the three-year-old is set to miss a large bulk of the campaign.
Gold explained: "He was re-X-rayed over the weekend and they found a crack in his off-fore cannon bone. He's had two screws put in it.
"He's going to need three months' recuperation. I can't tell you how long it will take for the bone to heal, but there will be nothing happening in the short term, obviously.
"It's disappointing, but better to find out this way than running down the hill at Epsom."
Meanwhile, Outspoken is set to be part of Aidan O'Brien's formidable squad for Royal Ascot later this month after his impressive debut at Navan.
The stoutly-bred son of Galileo made a big impression when making a successful start to his career, pulling readily clear of a number of more experienced horses in the hands of the trainer's son, Donnacha.
While that victory came over a mile and a quarter, Outspoken could step up to two miles for the Queen's Vase at the Royal meeting, with the King Edward VII Stakes over a mile and a half another option.