Grands Crus and Invictus are among 16 horses still engaged in the RSA Chase at Cheltenham.
Trainer Alan King revealed on Thursday that the former would still be entered in the Grade 1 contest despite suffering a late setback that could see him ultimately ruled out on the day.
Grands Crus still holds the option, although David Pipe has yet to decide whether or not he runs in the Gold Cup.
Nicky Henderson's Bobs Worth is likely to go off favourite if Grands Crus is absent. Henderson has also left in Mossley.
Willie Mullins has left in Sir Des Champs, who also has the option of the Jewson Novices' Chase, with stablemates Call The Police and Lambro also engaged.
First Lieutenant, winner of the Neptune last year, could run for Mouse Morris, while Join Together is Paul Nicholls' sole hope.
Tony Martin has surprisingly left in Bog Warrior, who is due to run at Naas at the weekend, along with Gift Of Dgab.
Mr Moonshine, Cannington Brook, Benbane Head and Saint Are complete the list.