Tyrone suffered a massive blow last night with confirmation that ace attacker Connor McAliskey has suffered a ruptured cruciate ligament.
The 26-year-old will miss the entire season as he undergoes surgery followed by a lengthy recovery and rehab process.
His worst fears were confirmed by the results of an MRI scan he underwent at the Ulster Clinic in Belfast earlier in the day.
The Clonoe clubman was stretchered off after colliding with an opponent in the second half of Sunday's Dr McKenna Cup defeat to Cavan at Kingspan Breffni Park.
The loss of McAliskey, one of the county's leading forwards, is a serious blow to Red Hand prospects for the season ahead. He was his side's top scorers in the 1-13 to 0-12 loss to the Breffni men with five points, before suffering the injury to his left knee in the 62nd minute.
Apart from Tyrone's first defeat in the competition in six seasons, Sunday's reversal came at a heavy cost in terms of injuries.
Michael Cassidy suffered a hamstring injury just 15 minutes into his debut, while Rory Brennan and Ronan O'Neill also picked up knocks which could rule them out of next weekend's meeting with Ulster University at Healy Park.
Meanwhile, Michael Murphy is to spend time with French rugby outfit Clermont Auvergne in the coming weeks as part of the latest instalment of the AIB documentary series The Toughest Trade.
Wales rugby legend Shane Williams arrived in Donegal where he will play with Murphy's club Glenswilly.