Uruguay coach Oscar Tabarez insisted it was "too harsh" to say Ghana had been cheated out of a place in the World Cup semi-finals.
A handball on the goalline by Luis Suarez prevented Ghana's Dominic Adiyiah from scoring in the last minute of extra time, and Asamoah Gyan missed the penalty -- with Uruguay triumphing in the shoot-out that followed.
The South Americans' goalkeeper, Fernando Muslera, was the hero, saving twice in the shoot-out, from centre-back John Mensah and Adiyiah.
Sulley Muntari, almost sent home earlier on in the tournament after a bust-up with Ghana's Serbian coach Milovan Rajevac, had given his side the lead before Diego Forlan equalised in normal time with a swerving free-kick for his third goal of the finals.
Tabarez claimed Ajax striker Suarez, who was subsequently sent off for his handball, had reacted instinctively.
He said: "When there is a handball in the penalty area there is a red card and the player is thrown out of the game.
"Saying we cheated Ghana is too harsh a word to use. We also abide by what the referee did. It could have been a mistake. Yes he stuck his hand out but it's not cheating. I don't think it's fair to say that.
"I think it was instinctive. The player instinctively reacted and was thrown out of the match, and he can't play the next match. What else do you want?
"Is Suarez also to blame for Ghana missing the penalty? We try to be dignified, and if we lose a match we look for the reasons for it. You shouldn't look to third parties.
"This is football. There are consequences to that handball and he didn't know that Ghana was going to miss that penalty."
For Uruguay, it confirmed their first semi-final appearance for 40 years -- they play the Netherlands in Cape Town on Tuesday -- and the result sparked joyous celebrations in the country.
Tabarez added: "I hope the party goes on for three or four days!
"I am the coach of the team, I'm a pro and even so I lack the necessary calm to carry out an objective analysis of what happened.
"We achieved our goal but we didn't play as we wanted to. Our rival was extremely tough. We were lucky. Luck is important and I really cannot say much more.
"Those who believe in fate or destiny, they might be able to explain it. I don't believe in that."
Ghana coach Rajevac hailed his heroic Black Stars and blamed a "sporting injustice" for their agonising exit.
Rajevac said: "There are no words to express what we feel. This is sport's injustice but I congratulate Uruguay -- they were the lucky ones. We had bad luck, that's all I can say."