Arsenal have suffered mixed fortunes ahead of their clash against Bolton with the return of Samir Nasri soured by the loss of winger Theo Walcott for up to six weeks.
Walcott, 21, is out of action following an ankle injury he sustained on international duty with England in midweek.
"Samir could be involved against Bolton," said Wenger.
"He has had a very good preparation and joins in training tomorrow."
Turning to Walcott's injury, Wenger added: "The tackle looked quite bad.
"When you see how it turned his ankle I thought it would be three or four days or it would be four to six weeks. Unfortunately, it will be four to six weeks."
Wenger will be also be without Robin van Persie for a similar length of time but Johan Djourou and Denilson are available after injury while new signing Sebastien Squillaci could make his debut.
The Gunners are still without striker Nicklas Bendtner, who is thought to be at least a month away from returning from a groin problem.
Meanwhile, Bolton boss Owen Coyle is preparing to nullify the threat of Jack Wilshere.
The 18-year-old has been an ever-present in the Gunners first team so far this season, and won his first senior cap for England in last month's friendly win over Hungary.
Coyle knows all about his ability following his loan spell at the Reebok last season.
"Jack is a very talented player. He is such a gifted lad and has matured no end," said Coyle.