West Ham's memorable win over Tottenham came at a cost with more injury worries for manager Slaven Bilic.
The Hammers could be without up to seven senior defenders when they head to Everton tomorrow.
James Collins is the latest casualty after suffering a hamstring injury, while Angelo Ogbonna had his ankle heavily strapped after limping through the second half.
Already missing Winston Reid, James Tomkins, Joey O'Brien and Carl Jenkinson due to injury and Sam Byram through suspension, West Ham finished the 1-0 victory with a makeshift back three of Ogbonna, youngster Reece Oxford and midfielder Cheikhou Kouyate.
Reid is the closest to returning following a hamstring problem but is short of match fitness, while Wales international Collins now faces a spell on the sidelines.
"It's his hamstring and it's not a couple of days (out)," said Bilic. "We will wait until it settles down and assess it. The first information is that we should be happy if he only misses three games."
On the clash with Everton, Bilic said: "We just want to work for each other and it shows on the pitch.
"We believe we can go anywhere and get a result. We will now head to Everton and not go for a point, we will go for the three points and see what it happens."