ST Mary's will look to impress in front of what should be a bumper crowd as they start the push for a top-three finish. Champions Belvo' might be able to call on the services of their Leinster number eight Leo Auva'a to help the league's second best attack.
St Mary's College v Old Belvedere, Templeville Road, Friday 7.30.
Blackrock College v Cork Constitution, Stradbrook
It doesn't get any easier for 'Rock. There is internal strife within the club that has not been helpful.
Clontarf v Shannon, Castle Avenue
First choice tight-head Niall Treston is back from injury to enhance'Tarf's scrum.
Young Munster v Lansdowne, Clifford Park
Leaders YM will be in a no-nonsense mood to deal with a Lansdowne club that has amassed the highest points total in the Division, thanks largely to fly-half Craig Ronaldson.
UCD v Galwegians, Belfield Bowl
Leinster lock Mark Flanagan should be available and Ireland U20 hooker David Doyle is back from injury.
Terenure College v DLSP, Lakelands Park
'Nure should have plenty of motivation for this one. Salmo coach David Murphy plots their fifth win in six rounds.
Old Wesley v Clonakilty, Donnybrook
Coach Morgan Lennon has promoted flanker David O'Connor, scrum-half Dan van Zyl and wing Ross Barbour.
Greystones v Instonians, Dr Hickey Park
Wing Ronan Carroll returns from injury in early October to add speed around the outside of the 'Stones attack.
Bective Rangers v Thomond, Donnybrook, (Sunday)
Rangers will have to rid themselves of inconsistency.
City of Derry v Seapoint
JP Finlay in the second row as the only change to the Seapoint side.
Midleton v Dublin University, Towns Park
Director of Rugby Tony Smeeth will want his players to bounce back from a comprehensive defeat to UCD.
Boyne v Banbridge, Drogheda
Coach Craig McGrath has put his trust in an unchanged side to thwart the threat of their third-placed opponents.
Naas v Sligo, Forenoughts
Player/coach Niall Carson makes two changes to the backline bringing Osam Farag in at full-back and Martin O'Neill into the centre.
Navan v Cashel, Balreask Old
Coach Leo Jordaan will have close to the same team again to attempt to administer leaders Cashel's first defeat.
NUIM Barnhall v Armagh, NUIM Maynooth
Barnhall make three changes with full-back Ryan Hopkins, hooker Padraic Beatty and flanker Tom McKeown.
Rainey Old Boys v Suttonians, Hatrick Park
Andrew Hegarty and Seamus Cantillon are introduced into the Suttonians' back row.
Ards v Wanderers, Hamilton Park
This is a critical contest between the bottom two.
Compiled by Des Berry