Severe allergic shock and seizures were reported as side effects during the first year of the HSE Cervical Cancer vaccination programme for schoolgirls.
An overview report by the Irish Medicines Board said an estimated 159,000 doses of Gardasil have been distributed since the launch of the programme in May of last year.
Reports of "adverse events" after giving the vaccination included six cases of anaphylactic shock in patients and five reports of seizures.
The board's members said that while they received 416 reports of side effects, overall "the balance of benefits and risks for the vaccine is positive".
The report points out that "anaphylaxis is a very rare side effect of most vaccines" and that all of the patients recovered following treatment.
In the case of the seizures, two were in patients with epilepsy, one of whom had been diagnosed just prior to vaccination.
According to the IMB review, the majority of the side effects reported were "non-serious and consistent with the expected pattern of adverse effect for the vaccine, as described in the product information".
Most of the reports related to dizziness with or without a headache.
It warns that in relation to anaphylaxis "appropriate medical treatment and supervision should always be readily available in case of a serious allergic reaction and possibly a rare anaphylactic event following the administration of the vaccine".
The board said the first year of the Schools Immunisation Programme was now complete and the experience "has been consistent with the known safety profile of the vaccine".
It said the IMB will no longer publish regular monitoring updates on its website although it will "continue to monitor the national experience with the use of Gardasil in the context of global safety data".
The board will also continue to collaborate with the EU and international counterparts in the evaluation of these data "communicating nationally as necessary".
To date no new risks have been identified for Gardasil during monitoring of national use.
Each year in Ireland around 250 women are diagnosed with cervical cancer and 80 die from it. At least 70 of these cases are linked to Human Papilloma Virus (HPV). Gardasil is a vaccine against HPV.
The HPV vaccines only protect against 70pc of cervical cancers so medical advice is that girls vaccinated in the HPV programme should also avail of smear testing offered by the Cancer Screening Service when they are older.
The Government first announced in August 2008 that all girls aged 13-15 would be given the vaccine, but later backtracked because of Budget cuts. However, in January of last year then Health Minister Mary Harney announced the programme for the second time, citing better prices from the medical suppliers.