Blue Insurance will create 100 jobs over the next two years as part of the company's expansion into the personal and international insurance markets.
The company will be employing staff across numerous departments including call-centre customer services, IT developement, junior management and administrative levels in its Dublin office. The expansion will see the numbers rise from 45 to 145 employees.
Blue Insurance was formed in October 2003.
The company has 160,000 existing Irish customers and more than 200,000 UK customers across its 14 brands.
Tanaiste Joan Burton said it was "fantastic news" for Blanchardstown and the surrounding area.
"Blue Insurance is an indigenous company that is competing and winning in the most competitive and sophisticated online insurance market globally, the UK," Ms Burton said.
"It is a young company that rewards its employees for imaginative thinking."