Fáilte Ireland fears a supervised injection facility in the capital will increase crime and anti-social behaviour and could harm the growth of tourism in Dublin city centre.
A submission made to the city council stated a considerable amount of top tourism destinations are near Merchants Quay, where the centre is proposed to be based.
Last month, Fáilte Ireland said it had concerns over the location but was not against the facility.
Those in the tourism industry were worried that such a facility would encourage further anti-social behaviour and crime.
Fáilte Ireland spoke of the efforts to grow tourism further in Ireland and of the major attractions that are all near Merchants Quay.
It was highlighted that some 1.7m people visited the Guinness Storehouse in 2017, with a further 603,000 taking in St Patrick's Cathedral, 371,000 at Dublin Castle, 238,000 at Christ Church Cathedral and another 200,000 to Dublinia.
"The tourism industry in the area of this proposed national facility have raised their concerns that the proposed Medically Supervised Injecting Facility may encourage crime and anti-social behaviour within this key tourism hotspot and may have a negative impact on their business and the safety of their staff," the submission read.