Wednesday 12 December 2018

Ovarian cancer passed on from father's genes

Genes: father’s role
Genes: father’s role

Ovarian cancer can be passed on to women by their fathers, scientists have established.

New genetic research has shown how some sets of sisters share a higher risk of developing the disease than their mother.

Ovarian cancer - often described as a "silent killer" - is the fourth most deadly form in the UK, claiming around 4,100 lives a year of 7,400 cases diagnosed. Half of all cases are found in women aged 63 or older.

The new study found those who inherit the genes for the disease from their father tend to develop symptoms six years earlier than those who inherit them from their mother.

The disease can be particularly dangerous - it has a 46 per cent five-year survival rate - because symptoms tend not to present until the cancer has spread beyond the ovaries, making it harder to treat.

The discovery should allow more lives to be saved with better family history screening, and eventually genetic tests.

Sunday Independent

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