Hot flushes to get the cold shoulder as non-hormonal drug on the way
A new drug could put an end to the curse of sweaty sleepless nights for women plagued by hot flushes.
New research shows that a "game-changing" experimental drug can cut flushes by up to 73pc in women going through the menopause.
Scientists hope the early stage study will lead to the first effective non-hormonal treatment for the unpleasant symptom that can be a nightmare to live with for some sufferers.
Hot flushes are linked to low levels of the female hormone oestrogen and typically accompany the menopause at around 45 to 55 years of age.
For many women, they may be little more than an uncomfortable inconvenience. But for others, frequent severe flushes can lead to numerous changes of clothing, bed sheets drenched in sweat and severely disrupted sleep.
The new drug, so far only known by its code name MLE4901, blocks a brain chemical called neurokinin B (NKB) that is linked to hot flushes.
The research was led by Professor Walijit Dhillo at the Imperial College London.