Actress Alison King who plays Carla Connor in Coronation Street is taking a break from the soap for "creative reasons" next year.
She has told producers that she wants "to try her hand at other projects" before returning to the dramas in Weatherfield.
Writers will now come up with an "enthralling exit" for the character who has been a regular in the ITV soap for nine years, according to a Coronation Street spokesman.
The mini-bus crash and her brother Rob's handover to the police after Tina McIntyre's murder are among the big stories in which King has recently appeared.
Since arriving the cobbles on 2002, Carla has had her fair share of bad luck.
Two of her husbands have died, her third - Peter Barlow - was wrongly imprisoned for Tina McIntyre's murder. She has also been the victim of rape and was once held captive.
Last night, viewers saw her blossoming romance with bistro owner Nick Tilsley come to a shuddering halt after the restaurateur told her his one time flame Erica is pregnant.
A Coronation Street spokesman said: "Alison King has indicated to producers that she would like to take a sabbatical from the show for creative reasons at some point in 2016.
"She wishes to try her hand at other projects before returning to the part of Carla Connor, a role she has enjoyed playing for nine years.
"Before Ali takes her break, Carla has much more drama to come. At the end of this month, she will be central to the explosive storyline which sees Victoria Court go up in flames, and the aftermath of that plotline will have huge consequences for the factory boss.
"Ali's desire to take a break from the show gives the writers the opportunity to come up with a enthralling exit for the character."