Russell Brand and Coldplay will be performing at The Secret Policeman's Ball - in New York.
The British-based fundraising show takes place in the US in March.
Jon Stewart, Stephen Colbert, and Mumford & Sons are among the other acts who have signed on for the event at Radio City Music Hall on March 4.
The concert will benefit Amnesty International, as it has since it started back in 1976 with celebrities like John Cleese.
Over the years, Bono, Sting and others have participated.
This will mark the first time it's being held in New York City.
The last Secret Policeman's Ball was in 2008 in London.
Amnesty International spokesman Andy Hackman says the organisation wanted to do something special for its 50th anniversary.
David "DJ" Javerbaum, the former head writer and executive producer for The Daily Show with Jon Stewart, said the show will feature sketches, music and more.