Comic Russell Brand said he will probe the Dalai Lama about the meaning of life when they share a stage together - and predicted: "Something crazy will happen."
Brand will act as master of ceremonies when the Tibetan spiritual leader addresses thousands of young people in Manchester later this week.
He said today: "I introduce him, and then I'll moderate. It'll be brilliant. I can't wait.
"I've never met the Dalai Lama and it's a great honour to meet someone who has dedicated their life to spirituality and to what he believes in his national situation there."
The funnyman turned movie star has been a vocal supporter of the Tibetan cause, often peppering his old Radio 2 show with cries of "free Tibet".
Speaking about his planned collaboration with the 76-year-old, Brand said: "I do have a question for him. Tell me the secret - what is it? What is the answer? Why are we here? Why are we alive? What is consciousness?
"Why do we know we're awake and the cat not knows it's awake? Why do we have this awareness? What is the connection between all of us? What is intuition? What is love? How are these things happening? I want to know all that.
"I'll do it in the last question. Also, can West Ham stay up?" he joked.
The Dalai Lama, who established the Tibetan government in exile in northern India's Dharamsala, is delivering a talk, which is free to the under 25s, at the MEN Arena on Saturday June 16.
Speaking as he promoted his new movie Rock Of Ages, Brand said he was "just going try to be myself with his Holiness".
Asked whether he would sing while they were on-stage, he said: "I think I can do True by Spandau Ballet."
Brand plays club worker Lonny in the movie - based on the soft rock stage comedy - which is out this week.