Emma Stone is reported to have signed up to play Mary Jane Watson in the Spider-Man reboot.
Sony Pictures Entertainment "will imminently offer the role" of the webbed superhero's love interest to the US actress, who starred in Zombieland and Easy A, reports Deadline.
The search goes on for Gwen Stacy, Peter Parker/Spider-Man's first love, who was played by Bryce Dallas Howard in Spider-Man 3.
The website said that Glee's Dianna Agron (Quinn Fabray), Mia Wasikowska (Alice In Wonderland), and newcomers Georgina Haig and Dominique McElligott are in the running for the coveted role.
Andrew Garfield will be portraying Spider-Man in Marc Webb's 3-D reboot of the superhero franchise, which is due for release in summer 2012.