JO Brand, the comedian, has been accused of doing "serious damage" to the reputation of Streatham after describing the south London suburb as a "----hole".
Her comment, during an edition of the BBC Two panel show Have I Got News For You, prompted a furious letter of complaint from a member of the local council.
Angelina Purcell, who goes by the title of “Streatham Town Centre manager”, said the “flippant” remark had made her job “ten times harder”.
In a 300-word complaint letter, she said Brand had “let herself down badly” with her comment on Sunday night's edition of the popular BBC One programme.
Purcell, who works for Lambeth Council, said: “You clearly do not understand the serious damage your flippant comment has had on our collective efforts to transform Streatham's image.
“Together with the committed people of this town we continue to make strides in reversing the town's economic decline.
“You've made my job ten times harder with the use of one word and I'm sure the 60,000 residents and 3,000 businesses feel just as angry as I do.
“For us, you've let yourself down badly Jo and I hope you'll think twice about doing something like this again.”
Famous former residents of Streatham include Ken Livingstone and Naomi Campbell. Cynthia Payne, the brothel madam, brought the area to national attention in 1978 when police raided her home at 32 Ambleside Avenue and found a sex party in progress, at which patrons paid for services in luncheon vouchers.
Sir Roger Moore lived in Streatham in his pre-Bond years, although he now prefers to divide his time between Switzerland and Monaco.
Brand referred to the area during a discussion with the panel, pointing out that Streatham High Road was voted the Worst Street in Britain in a 2002 BBC poll and adding: "Don't go there."
Her spokeswoman said there was “no serious intent” behind the joke.
She said: “When Jo is on tour she says this about every place she goes to and she has never had any complaints yet. Most people have a sense of humour about where they live.
“It was just a throwaway remark which is no way was supposed to have any serious intent behind it.
“As for some people not finding it funny, we'll take your word for it and she won't 'diss' Streatham again in this way. We sincerely apologise for any offence that may have been caused.”