AstraZeneca takeover: 'Opportunistic bid' from Pfizer risks R&D disruption
* Pfizer hints at improved offer if AstraZeneca engages
* Read says can't commit to specific research spend
* AstraZeneca says "opportunistic" bid risks R&D disruption
* But AZ CEO says cannot rule accepting compelling offer
* Head of Unite union says members "very, very concerned"
U.S. drugmaker Pfizer hinted it could raise its proposed $106bn offer if AstraZeneca would only engage in talks, as its boss was grilled by UK lawmakers on his commitment to British research spending and jobs.
In response AstraZeneca said it would have to consider a compelling offer but accused Pfizer of an "opportunistic" proposal with a ploy to cut taxes that risked its reputation.
Pascal Soriot, the French-born boss of AstraZeneca, came out fighting after Pfizer's Chief Executive Ian Read made clear the New York-based group would not rule out a hostile bid if Britain's second-biggest drugmaker did not enter merger talks.
Having warned that AstraZeneca could wither without its financial muscle, Pfizer expressed its frustration at being rebuffed, and said on Tuesday that working with the UK company's board could help deliver "optimal deal terms" which AstraZeneca could recommend to its shareholders.
Soriot - who appeared after Read to answer questions from a parliamentary select committee - said Pfizer's proposal risked disrupting its research and development work and delaying getting life-saving new drugs to market, as well as undervaluing the business.
"What will we tell the person whose father died from lung cancer because one of our medicines was delayed - and essentially was delayed because in the meantime our two companies were involved in saving tax and saving costs?" he asked lawmakers.
Pfizer's plan to cut its tax bill by re-domiciling to Britain if it buys AstraZeneca also posed a reputational risk, Soriot added.
"The proposed tax inversion structure, we are afraid, could generate substantial controversy and potentially delay this merger and potentially impact the reputation of our company."
AstraZeneca rejected Pfizer's May 2 cash-and-stock offer worth 50 pounds a share and said it had a bright future as an independent business. But by midday on Tuesday its shares had risen 1.5 percent on anticipation it would have to consider another proposal.
"If Pfizer continues to aggressively pursue the deal by raising the price, then AstraZeneca's board would have to little choice but to engage," said Ketan Patel, an analyst at Ecclesiastical Investment Management, a holder of AstraZeneca shares.
Pfizer is widely expected to come back with a sweetened offer for AstraZeneca this week, although people with knowledge of the matter said it was likely to wait until after the parliamentary hearings to make any new move. Both chief executives, who gave confident performances, will appear before another panel on Wednesday to answer questions about the science aspects of the deal.
"Engagement would provide AstraZeneca management with the opportunity to provide Pfizer a better understanding of the business and its prospects, and the credible basis for their new long-range targets," the U.S. company said in a statement early on Tuesday. "Pfizer will continue to be disciplined on price."
Pfizer's bid would be the largest foreign takeover of a British firm and is opposed by many scientists and politicians.
Parliamentary select committees cannot block corporate transactions but they can question executives ferociously, as banks, energy companies and Rupert Murdoch's News Corp have all found out: The media coverage resulting from these sessions confirmed them as corporate bad guys for much of the public and placed future dealings under even closer scrutiny.
NO SPECIFIC BUDGET
Pfizer already has a tarnished reputation in Britain after shutting down most of its research in southern England where Viagra was invented, with the loss of some 1,700 jobs.
Now it faces scepticism about its long-term commitment to AstraZeneca, though Read told the panel: "I'm a man of my word."
Pfizer has given a five-year commitment to complete AstraZeneca's new research centre in Cambridge, retain a factory in the northwestern English town of Macclesfield and put a fifth of its research staff in Britain if the deal goes ahead.
Having pledged to keep a fifth of research jobs in Britain, Scottish-born Read said he could not commit to maintaining a specific R&D budget there.
"We'll be efficient by some reduction in jobs. What I cannot tell you is how much or how many or where. We'll look at this as our global combined footprint and then we'll make decisions," Read said.
He told the panel he expected the combined research expenditure of the merged drugmaker would be lower than that of the two separate companies, noting one of the drivers of his proposed deal was to increase efficiency to keep both firms competitive in an increasingly tough marketplace.
Read also came under fire over the ethics of re-domiciling in Britain, for tax purposes only, in order to cut its tax bill - a move that has sparked anger as well in the United States, where the taxman stands to lose out.
Allan Black, national officer for the GMB trade union, told the select committee: "Worryingly, the lawyers we've consulted don't see any obvious mechanism to make a five-year commitment binding."
Unite, Britain's biggest trade union, ran an advertisement in the country's biggest free morning newspaper Metro on Tuesday, saying Pfizer was "the wrong prescription for Britain."
Tony Burke, Assistant General Secretary of Unite, said his members were "very, very concerned" about Pfizer's record of cutting 65,000 jobs worldwide since 2005.
AstraZeneca pushed out details on its new drug pipeline late Monday and early Tuesday morning, flagging good news on drugs for asthma, rheumatoid arthritis, lupus and diabetes to prove it can stand on its own.
In Tuesday's sessions lawmakers will also interrogate business minister Vince Cable. Then a second parliamentary committee on May 14 will question both CEOs again, along with British science minister David Willetts, about the science aspects of the deal.