An average of 71 companies were set up every day in Ireland during the first three months of 2019.
This is despite Brexit uncertainty and concerns about a slowdown in the global economy.
The largest number of companies was founded in the professional services sector, according to figures from business information company CRIF Vision-Net.
The construction sector also reported a modest increase in new businesses, however there was a slight drop in the number of finance firms being set up here.
"The buoyant entrepreneurial spirit in Ireland continues to weather the continued uncertainty across the water," said Christine Cullen, managing director of CRIF Vision-net.
Ms Cullen said the first quarter of 2019 has been "the best in 13 years" for start-ups.
Meanwhile, last year saw an almost 26pc year-on-year drop in insolvencies versus 2017.
In the first three months of 2019 there were 192 insolvencies, an average of two per day.