Graduates from Trinity College founded more venture-backed companies than graduates from any other European university over the last 13 years.
Trinity sits at number 46 in the global rankings for producing venture-backed entrepreneurs from its undergraduate programmes, according to research from US-based data company Pitchbook.
The university's ranking is up two places from last year.
Between 2006 and 2018 Trinity alumni produced 232 entrepreneurs, formed 212 venture-backed companies, and raised capital of approximately $3.26bn (€2.8bn).
Among the notable Trinity graduates who are leading companies are Intercom founders Eoghan McCabe and Ciaran Lee. Intercom's customer engagement platform recently achieved unicorn status when it was valued at over $1bn.
Another success story is Dr Nora Khaldi, founder of Nuritas, which raised €20m in March for its artificial intelligence and genomics platform that discovers and unlocks natural bioactive peptides with extraordinary health benefits.
"Trinity has placed innovation and entrepreneurship at the heart of its strategy," said chief innovation and enterprise officer Dr Diarmuid O'Brien.
"The news that Trinity is again Europe's leading university for graduate entrepreneurship further supports these ambitions and our role as a global leader in enabling the best students to become the best entrepreneurs."