A suckler cow from a farm in Galway has tested positive for 'Atypical BSE', but officials insist it won't affect the vital beef export trade.
The Department of Agriculture said the 18-year-old suckler cow had come to its attention through its surveillance of 'fallen' animals which are taken to knackeries.
While the animal tested positive, the department said there are no associated public health risks.
It is different to the 'classic' BSE of the 1980s which was known as 'mad cow disease'.
Ireland's last BSE case was in 2015 and there was no serious impact on trade.
This case of Atypical BSE, the department says, will not affect Ireland's official BSE-controlled risk status or trade status.
The news came on the same day that a third case of bird flu, in wild birds, was identified in Ireland. A whooper swan, found in Borrisokane, Tipperary, was identified as having avian flu yesterday.
After the second case was confirmed in December, the department emphasised the requirement to confine poultry and other birds, and to apply strict bio-security measures to prevent the introduction of avian influenza.