A Burmese Python was found abandoned in the Wicklow Mountains National Park over the weekend.
The five-foot long snake, named Sammi by wildlife rescuers, was discovered by a local farmer.
It was underweight, dehydrated and injured and has since been placed in the care of a reptile specialist.
The ISPCA said the discovery is concerning and its concerned about the care it was receiving prior to being abandoned.
“In addition to the potentially illegal release of a non-native species, there are numerous possible offences under the Animal Health and Welfare Act 2013," a spokesperson said.
"This snake did not make its own way up the Wicklow Mountains and we believe that it was abandoned and left in an environment not suited to an animal of this type. We suspect that it had been abandoned some days prior to her discovery."
Sammi is "hanging in there" but the ISPCA are unsure if she will pull through.
The organisation is calling for stronger regulations around the breeding, keeping and selling of exotic animals as pets.
Anyone with information about Sammi is asked to call the ISPCA National Animal Cruelty Helpline on 1890 515 515 or email us at email@example.com in confidence.