Three children have died and two adults have been injured after a car crashed and overturned on the M6.
The two boys and one girl were confirmed dead at the scene of the crash which happened near to junction 15 of the northbound carriageway in Staffordshire at about 11.25am, West Midlands Ambulance Service (WMAS) said.
Two adult women who were also in the car were taken to University Hospital North Staffordshire for treatment.
The WMAS spokesman said: “Crews arrived to find a single vehicle that had crashed and overturned.
“Three children that were travelling in the vehicle suffered serious injuries.
“Unfortunately, despite the best efforts of ambulance crews, nothing could be done to save the two boys and one girl, and they were confirmed dead at the scene.
“Two adult women travelling in the car, both received emergency treatment at the scene for their injuries and were transferred by land ambulances to University Hospital North Staffordshire on blue lights for further treatment.”
He added: “All emergency services personnel worked seamlessly together at the scene in exceptionally difficult circumstances.
“Unfortunately, the outcome was not the one everyone would have hoped for.”
Two Midland Air Ambulances and three ambulances attended the scene, which closed the motorway in both directions for several hours.
In a separate incident, a couple were killed after being taken for a drive by their son shortly after 10am on Christmas morning.
The husband and wife died when the silver coloured car veered off the road near a bend and crashed into trees before flipping onto its side on the B3349 Odiham Road at Riseley, Berkshire, on the border with Hampshire.
The driver, a young man aged in his 20s and believed to be the dead couple's son, suffered serious chest injuries and was taken to hospital.
Earlier, a man was injured after his vehicle split into at least three pieces following a collision between junctions 5 and 6 eastbound on the M6 Toll at around 3.35am.
The man, in his mid-20s, suffered multiple minor injuries and was taken to hospital for treatment.
A spokesman for West Midlands Ambulance Service (WMAS) said: "Crews arrived to find a car that is believed to have been in collision with road signs and a bridge and suffered substantial damage, splitting into at least three pieces.
"The driver of the car, a man in his mid-20s, was found on scene and had suffered multiple minor injuries, but was extremely disorientated.
"He received emergency treatment at the scene and his condition was stabilised.”
He was taken to University Hospital North Staffordshire for further assessment and treatment, the spokesman said.
"Considering the damage to the vehicle, the man was extremely fortunate not to have suffered more serious or even fatal injuries."
On Christmas Eve, a man suffered life-threatening injuries after he was in collision with a herd of horses running loose on a dual-carriageway.
The victim, who was in his 20s, was driving along the A14 on the outskirts of Ipswich,. Suffolk, just after 10.00pm on Christmas Eve when the horses which had escaped from a nearby field galloped onto the road.
The driver and three other vehicles were unable to avoid the animals and hit them, killing three.
A 26-year-old local man - believed to be the owned of the horses - was arrested on suspicion of causing danger to road users.
And in another crash, an elderly couple died and a second driver was seriously injured after a head-on collision.
One of the victims was trapped as both the cars burst into flames after the crash.
A 76-year-old woman passenger in the Astra, believed to be from the Leicester area, was declared dead at the scene and the 77-year-old driver, believed to be her husband, later died in hospital.
The 69-year-old woman driver of the Polo who is from the Norwich area suffered two broken legs, a broken right arm, broken pelvis and internal bleeding.
By Wesley Johnson Telegraph.co.uk