Seven people were taken to hospital when a caravan hit a group of pedestrians.
Officers were called to Beer in Devon at 11.10 today to reports of the "serious collision".
One pedestrian who suffered serious injuries has been taken to Derriford Hospital in Plymouth by air ambulance.
Six other casualties,- including the driver of the caravan, are being taken to the Royal Devon & Exeter Hospital in Exeter for treatment.
A spokesman for Devon and Cornwall Police said four pedestrians were teenagers, three females and one male.
He added: "Police have been called to a serious collision in Fore Street, Beer.
"Officers were called to the scene, near the Anchor Inn, at 11.10am this morning after reports a campervan or caravan has collided with a group of pedestrians.
"At this early stage their injuries are not thought to be life threatening.
"Fore Street is closed at Long Lane and what is described as the top end of Beer."
It is understood the caravan could have been travelling the wrong way down a narrow one-way street when the accident happened.
The foreign vehicle struck a wall before ploughing into the group of pedestrians, including four teenagers, and came to a stop.
The driver of the vehicle, a German national, provided a negative breath test at the scene and is being treated at hospital.
A spokesman for South Western Ambulance Service NHS Foundation Trust said five ambulances and an air ambulance had attended the incident.
He said: "At 11:06 today South Western Ambulance Service NHS Foundation Trust (SWASFT) was called to attend a serious road traffic incident involving a campervan in the Beer area.
"Five conveying resources were deployed to the scene along with a Basics doctor, the Devon Air Ambulance and further clinicians and resources from SWASFT's hazardous area response team.
"At this stage we can confirm that one patient has been taken by Air Ambulance to Derriford Hospital with a further six patients taken by land crews to Royal Devon & Exeter Hospital or treated at the scene."