The five-term senator and 2004 unsuccessful presidential candidate had broad support from fellow Democrats and Republicans in the Senate. As voting continued, he had received well over 60 votes in favor of his confirmation, and just two against it.
The full Senate is expected to confirm Kerry later on Tuesday.
The five-term senator and 2004 failed presidential candidate has broad support from fellow Democrats as well as Republicans in the Senate.
Meanwhile, LaHood said: "I have let President Obama know that I will not serve a second term as secretary of the U.S. Department of Transportation," LaHood said in a statement.
Obama has been under pressure to bring more women and minorities into his Cabinet.