Both are fervent supporters of Barack Obama, so much so that rumours have been swirling that Wintour may be after the diplomatic post of US ambassador to London - although the US Vogue editor has reportedly denied this.
Both The Guardian and The Independent have implied that Wintour's semmingly super-human fundraising abilities may just put her in line to succeed Louis Susman in the role of ambassador when he retires later this year.
Wintour has attended two state dinner's already this year, as well as spearheading Runway to Win , a collective of some of fashion's biggest names - including Marc Jacobs, Jason Wu, Alexander Wang and Diane von Furstenberg - which sells Obama-inspired designs.
Yesterday, Wintour was spotted making her way into Parker's brownstone as removal men transported various pieces of furniture in and out of the property, no doubt making way for the various stars expected to attend the event.
Earlier this month, the front-row friends made separate televised advertisements promoting the event and offering mere mortals a chance to win tickets to the fundraiser by entering a $3 raffle.
Meanwhile, Obama's wife Michelle has said she's not anticipating a fashion face-off with either SJP or Wintour, and will be wearing "jeans and some flats," she told TheInsider.com . She's a brave woman.
George Clooney hosted a similar event at his Los Angeles home last month which reportedly raised $15 million for the Obama campaign.