The model has signed up to pose for Playboy Europe for their Spring 2012 edition after previously resisting lucrative offers from the men's magazine.
She told the Sunday Independent: "When I'm old and wrinkly I'll have shots like these to look back on."
Davison, who struck the deal in recent days, is said to be in line for one of the biggest payouts of her career and will receive a six-figure sum for posing nude.
Playboy, founded in Chicago in 1953 by Hugh Hefner and his associates, is one of the world's most successful brands. Rosanna has received the "full support" of her singer father Chris De Burgh, former model mom Diane and long-term boyfriend Wesley Quirke.
"The shoot is going to get everyone talking," explained a friend. "Rosanna is no shrinking violet and it's going to be her sexiest shoot yet.
"She's an exhibitionist at heart and she's not shy about her body, so trust me when I say this is going to be one to remember."
Speaking about her family's reaction, the friend revealed: "Rosanna's parents met her manager and are perfectly happy about it. They advise her but would never interfere in her career choices. Wes is fully supportive too and is actually really proud of her decision."
The sultry catwalk model has recently hired a new European manager, who also represents Dita Von Teese, and he is behind the latest money-spinning deal.
Davison will now join the likes of Pamela Anderson, Marilyn Monroe, Betty Page, Kim Basinger, Denise Richards and Helena Christensen -- who have all previously graced the pages of the controversial men's magazine.
This weekend, the 27-year-old beauty was keeping coy about the deal, but when asked what fans can expect, she said: "I'll keep that a surprise until it comes out but it will be as tasteful as possible. I want it to be classy."
She continued: "It's my career and my decision; I would never judge others on what they decide to do. But ultimately, when I'm old and wrinkly, I'll have shots like these to look back on. I'm a big believer in taking opportunities in life and pushing boundaries."
She declined to say how much the deal was worth.
In recent months, the model has been working hard to build her profile in Europe, working with Grey Goose, Audi, and designers Susanne Wiebe and Gerry Weber.
Meanwhile, Playboy, which recently celebrated its 50th anniversary, is still the world's biggest-selling men's magazine, shifting millions of copies worldwide, with over two million copies of each issue sold in the US alone.
However, Rosanna's shoot will be featured in the European edition only.