The GI Jane actress, who announced her split from third husband Ashton Kutcher last November, apparently checked into the Monte Carlo Beach Club, a luxury hideaway in the capital city of the United Arab Emirates, reported USmagazine.com.
She was spotted lounging in a cabana overlooking the ocean with friends on November 3.
"Demi seemed to be enjoying herself - they all did," a hotel source told the website.
Ahead of her milestone birthday on November 11, Demi later flew to Jodhpur, India, to attend the two-day birthday bash Naomi Campbell threw for boyfriend Vladislav Doronin, which Kate Moss also attended.
Since confirming her separation from Ashton in November 2011, following rumours of his infidelity, the actress has preferred to stay away from the spotlight.
She has been filming her big-screen return in drama Very Good Girls alongside Elizabeth Olsen and Dakota Fanning.