Hewson (21) is enrolled on a prestigious New York University drama course and is living in the US city with her Irish best friend.
She described how the "greatest moment probably of my life" happened when Beyonce strolled by with her dad as she was in their pool.
She said: "I was with my friend Blue (The Edge's daughter) and we just went under water and screamed and then got out of the pool and hid. "So that's when we used Dad -- to get cute boys and Beyonce."
She said that Bono also got her and her older sister Jordan introductions to the hottest rock stars on the planet when they were growing up.
On meeting a member of Kings of Leon, she said: "We were like, 'Dad, who is that guy? Go and talk to him so we can meet him.'"
The beautiful brunette, who appears in the magazine's latest edition under the title 'Hot Rock Progeny', admitted it was sometimes hard to emerge from her father's enormous shadow.
"I feel like I should be constantly defending me, like I am my own person," she said.
"I definitely have his genes in the going-out department. It's dangerous."