American Girl in Paris
The 21-year-old model features in the French handbag brand's spring 14 advertisements and has struck an array of poses in New York for the finished shots.
One photo sees Karlie standing in front of several iconic yellow taxi cabs holding a beige bag, while another captures her leaning against a fence holding up a small black and white purse.
Evelyne Ling, director of the company's US operations, is pleased Karlie can help spread their name in the States.
It isn't just the advertising strategy Lancaster Paris has adapted. The label has also tampered with its design elements to give the brand a more competitive feel.
"We showed the collection to different people in the industry because we wanted to be sure we were making the right move," Evelyne added. "We had a great response, but also had to make some changes, like adding more colour. We really tried to take into account all the feedback."
Karlie seems proud of the new shots. The brunette beauty posted one of the photos on her Instagram account for fans.
"Excited to unveil my Spring 2014 Campaign for@LancasterParis (sic)" she wrote.
The bags Karlie models are sold in select designer boutiques across the US. Evelyne hopes Lancaster Paris can open a Manhattan flagship store in the near future.
"We're very confident that we can move forward quickly," she said.